Biological Applications of Integrative Manufacturing

Outline

Additive/Subtractive Biological Applications and Barriers

Surgical Planning

Tissue Engineering Concepts:

Tissue Engineering Challenges

Advantages of Add/Sub Mfg for Biological Applications

Challenges/Barriers for Additive/Sub Mfg

Summary: Biological Applications

Systems for Biomaterial Fabrication

SFF Systems used for Biomaterial Fabrication

Perfactory System Envisiontec

3D Bioplotter

Reactive Plotting in 3D Bioplotter

Biomaterials Processed on 3D Bioplotter

Freiburg/Envisiontec Bioplotter Applications

European Sites Fabricating Exterior Biomedical Devices

Hearing Aid Shells/Dental Ceramics

Hearing Aid Shells

European Sites Fabricating Hard Tissue Scaffolds

HA Bioplotter scaffolds postfab Sintered

Isotis (Netherlands) and Envisiontec

Loughborough Biological Applications

Loughborough: SLS of HA Implants

Loughborough: Fabricated HA Microstructure

University of Leeds – Mechanical Engineering

Fraunhofer Institute for Laser Technology, Aachen, Germany

Designed Spinal Fusion Cage – ILT and UMich

European Sites Fabricating Soft Tissue Scaffolds/Printing Cells

Polytechnic Institute of Leiria, Portugal

University of Manchester Institute of Science and Technology

3D Bioplotter

PLGA Melt Processed on 3D Bioplotter

Collagen Scaffold Processed on 3D Bioplotter

Fibrin Processing using Reactive Plotting

Schematic of Cell Printing using Bioplotter

Cells Printed in Agar Hydrogel

Conclusions

Conclusions

Future Issues

Biological Application Conclusions